Principal Bioinformatics Scientist


Impact Healthcare

Join our Software and Bioinformatics team and  leverage the latest advances in bioinformatics, data science and machine learning to support the Research and Development efforts for our acclaimed sample and library preparation reagents that bring precision to Next Generation Sequencing (NGS) and other omics applications. Apply your passion for informatics and data analytics to contribute to solutions that are transforming life science innovation and the actualization of personalised medicine.


Position summary

As a Principal Bioinformatics Scientist, you will provide bioinformatics support for product research and development, as well as the marketing, sales and on-market product support teams. You will collaborate broadly to develop and apply informatics, data analytics, computational learning and novel algorithms to NGS and other genomics inventions, investigations and products.



Partners closely with R&D teams to provide bioinformatics expertise including experimental design, data collection, QC, algorithm design, analysis and visualization
Proposes and builds novel data analysis methods or algorithms as needed
Negotiates complex issues with peers and partners, promoting cohesive teamwork
Collaborates across the Software and Bioinformatics organization to drive innovation and achieve shared goals
Stays abreast of developments in NGS technologies, analytics and applications and shares knowledge and expertise with others
Follows best practices for documentation and reproducible research
Provides bioinformatics leadership and mentorship on project teams or subteams to solve business-relevant problems of moderate size risk and complexity
Presents technical reports or summaries and delivers presentations to diverse audiences, including project teams, other departments, collaborators, and customers
Assists on-market support teams in training and handling customer enquiries as needed

Excellent organizational, interpersonal and communication skills, and able to work within in a cross-functional team environment, leading and/or influencing when appropriate
Able to work independently with minimal supervision; effectively planning, prioritizing and executing work assignments, using discretion and independent judgment within broadly defined practices and policies
Experience with NGS data analysis e.g. WGS, WES, RNA-Seq, and with general Bioinformatics tools, e.g. sequence alignment, variant analysis and database queries
Proficient in applying coding and software development best practices in a scripting or programming language such as Python, JAVA, R, C++, etc
Experience using a workflow management system, e.g. Snakemake, Nextflow, etc on top of a job scheduler in a Linux high performance computing environment, with cloud computing experience being a plus
Experience with code version control, e.g. GitHub
Excellent written and verbal English communication and scientific presentation skills
A PhD degree in Bioinformatics, Computational Biology, Computer Science, or a relevant subject area plus 4+ years of direct related experience, or a relevant Masters degree with 7+ years related experience

High proficiency in Python, with JAVA, R and Agile methodology experience being a plus
Strong statististics skills, with data science and/or machine learning experience a plus
Experience developing and applying Bioinformatics methods/systems
Experience leading or working in interdisciplinary teams
Roche is an equal opportunity employer.

Research & Development, Research & Development > Research Informatics
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Who we areAt Roche, 98,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer.
Job factsLocation South Africa, South Africa
Function Research & Development
Subfunction Research Informatics
Schedule Full time
Job level Individual contributor
Job type Regular
Division Diagnostics
Posted since 2020/08/24
Job-ID 202008-121833